{"product_id":"zonesun-zs-dm1-automatic-prefilled-syringe-denesting-machine","title":"ZONESUN ZS-DM1 Automatic Prefilled Syringe Denesting Machine for Syringe Filling Lines","description":"\u003ch2\u003eDescription\u003c\/h2\u003e\n\u003cp\u003eThe ZONESUN \u003cstrong\u003eZS-DM1\u003c\/strong\u003e is a \u003cstrong\u003efully automatic prefilled syringe denesting machine\u003c\/strong\u003e designed to remove syringes from \u003cstrong\u003enest tubs\u003c\/strong\u003e and transfer them one by one into downstream \u003cstrong\u003efilling and stoppering lines\u003c\/strong\u003e. It supports \u003cstrong\u003eBD, BG, SCHOTT, SCF\u003c\/strong\u003e, and other standard nest formats, with custom tooling available for special specifications. Built on a \u003cstrong\u003eSUS304 stainless steel frame\u003c\/strong\u003e with \u003cstrong\u003eSUS316L and medical-grade silicone\u003c\/strong\u003e product-contact parts, it meets stringent pharmaceutical hygiene and material standards.\u003c\/p\u003e\n\u003cp\u003eThe ZS-DM1 features a \u003cstrong\u003ePLC + touchscreen control system\u003c\/strong\u003e with real-time monitoring, fault detection, and alarm functions for simplified maintenance. Its \u003cstrong\u003emodular design\u003c\/strong\u003e supports both standalone operation and seamless inline integration with syringe filling and stoppering equipment. An optional \u003cstrong\u003eGrade A laminar flow hood\u003c\/strong\u003e is available for facilities requiring higher aseptic manufacturing cleanliness levels.\u003c\/p\u003e\n\n\u003ch2\u003eParameter\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMachine Model:\u003c\/strong\u003e ZS-DM1\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVoltage:\u003c\/strong\u003e 380V \/ 220V, 50\/60 Hz\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTotal Power:\u003c\/strong\u003e 0.8 kW\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplicable Syringe Specifications:\u003c\/strong\u003e 0.5–10 ml (Different specifications require mold replacement)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCompressed Air:\u003c\/strong\u003e 0.55–0.75 MPa, 15 L\/S\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMachine Size (L×W×H):\u003c\/strong\u003e 2230 × 900 × 1800 mm (Without laminar flow hood)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMachine Weight:\u003c\/strong\u003e 400 kg\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_01_ceed2d05-201f-4be6-b398-837b7b0be70a.jpg?v=1785465392\" alt=\"ZONESUN ZS-DM1 Automatic Prefilled Syringe Denesting Machine Overview\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_02_e89273c8-d78c-4208-94f7-5cd53b29faf5.jpg?v=1785465391\" alt=\"ZS-DM1 Syringe Denester Full System View\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_03_2aba303b-2dc1-4e7c-b32e-4ab1895a4b56.jpg?v=1785465392\" alt=\"ZS-DM1 SUS304 Frame and SUS316L Contact Parts Detail\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_04_2b843b1a-463d-48a3-8d64-b431bc3e7fda.jpg?v=1785465391\" alt=\"ZS-DM1 Nest Tub Loading and Syringe Extraction Station\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_05_8eabaa92-01c3-416c-b8d6-d251fc94915b.jpg?v=1785465392\" alt=\"ZS-DM1 PLC Touchscreen Control Panel and HMI\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"MsoNormal\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eAutomatic Syringe Extraction Unit\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eAutomatically removes prefilled syringes from nest trays and transfers them smoothly without damaging the barrels.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_06_7bf024eb-90a0-48b9-8b41-cc108a8d3e2c.jpg?v=1785465563\" alt=\"ZS-DM1 Automatic Syringe Extraction from Nest Tray\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"MsoNormal\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eTilting Discharge Mechanism\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eTilts the syringe holding assembly and guides syringes smoothly into the infeed rail of the downstream filling and stoppering machine.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_07_a6963ba3-e65c-425b-80db-92cd2e12c5cd.jpg?v=1785465563\" alt=\"ZS-DM1 Tilting Discharge Mechanism to Downstream Filling Line\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"MsoNormal\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eAseptic Glove Port Design\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eAllowing aseptic manual adjustments, sampling, and interventions through integrated glove ports without directly exposing the sterile process environment.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_08_8933eed2-dd0f-42c2-8f1d-0b28549b8ed1.jpg?v=1785465563\" alt=\"ZS-DM1 Aseptic Glove Port for Sterile Manual Intervention\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"MsoNormal\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eModular Control System\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eThe machine uses modular electrical components to simplify operation and integration with syringe filling, stoppering, and other pharmaceutical equipment.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_09_afdeca7e-2a93-4d94-abce-0759e4a6d9dc.jpg?v=1785465562\" alt=\"ZS-DM1 Modular Electrical Control System for Pharma Line Integration\"\u003e\u003c\/p\u003e\n\n\u003cp class=\"MsoNormal\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eOptional Grade A Laminar Flow Hood\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eAn optional Grade A laminar flow hood creates a localized clean airflow area above the syringe processing zone, helping meet higher aseptic manufacturing requirements.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_10_2aaff4b2-ef62-4304-9c9b-3a362f56fc8a.jpg?v=1785465563\" alt=\"ZS-DM1 Optional Grade A Laminar Flow Hood for Aseptic Processing\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0451\/6492\/0998\/files\/944_11_fe8320f1-dd4b-4880-8d3a-524120797b82.jpg?v=1785465563\" alt=\"ZS-DM1 Laminar Flow Hood Clean Zone Detail\"\u003e\u003c\/p\u003e\n\n\u003ch2\u003eKey Features\u003c\/h2\u003e\n\u003cp\u003e✅ \u003cstrong\u003eMulti-Format Nest Compatibility:\u003c\/strong\u003e Supports BD, BG, SCHOTT, SCF, and other standard nest tub formats, with custom tooling available for non-standard syringe specifications.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003ePharmaceutical-Grade Materials:\u003c\/strong\u003e SUS304 machine frame with SUS316L and medical-grade silicone product-contact parts, fully compliant with pharmaceutical hygiene and material standards.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003eGentle, Damage-Free Extraction:\u003c\/strong\u003e Automated extraction mechanism removes syringes from nest trays without contacting or stressing the barrel, preserving prefilled product integrity.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003eSmooth Downstream Transfer:\u003c\/strong\u003e Tilting discharge mechanism guides syringes directly into the infeed rail of filling and stoppering lines, ensuring continuous, jam-free production flow.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003eAseptic Glove Port Access:\u003c\/strong\u003e Integrated glove ports allow operators to perform manual adjustments, sampling, and interventions without breaking the sterile process barrier.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003ePLC + Touchscreen Control:\u003c\/strong\u003e Real-time monitoring, fault detection, and alarm functions simplify operation and reduce maintenance response time on the production floor.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003eModular Design for Flexible Integration:\u003c\/strong\u003e Operates standalone or integrates inline with syringe filling, stoppering, and capping equipment via modular electrical architecture.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003eOptional Grade A Laminar Flow Hood:\u003c\/strong\u003e Available upgrade for facilities requiring ISO 5 \/ Grade A localized clean airflow above the syringe processing zone.\u003c\/p\u003e\n\u003cp\u003e✅ \u003cstrong\u003eWide Syringe Size Range:\u003c\/strong\u003e Handles 0.5–10 ml prefilled syringes with mold changeover, supporting multiple product formats on a single machine platform.\u003c\/p\u003e\n\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePrefilled Syringe Filling Lines:\u003c\/strong\u003e Automated denesting and infeed of prefilled syringe barrels into filling and stoppering machines for injectable drug manufacturing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVaccine \u0026amp; Biologic Manufacturing:\u003c\/strong\u003e Aseptic denesting of glass and polymer syringes for human and veterinary vaccine filling under GMP-compliant conditions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsulin \u0026amp; Hormone Injectables:\u003c\/strong\u003e High-precision syringe feeding for small-volume parenteral (SVP) filling lines handling insulin, hormones, and other sensitive biologics.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOphthalmic \u0026amp; Specialty Injectables:\u003c\/strong\u003e Gentle extraction and transfer of delicate syringe formats used in ophthalmic drug delivery and specialty injectable products.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eContract Development \u0026amp; Manufacturing (CDMO):\u003c\/strong\u003e Flexible multi-format denesting for CDMOs handling diverse syringe specifications and frequent product changeovers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eVeterinary Injectable Packaging:\u003c\/strong\u003e Denesting and feeding of veterinary prefilled syringes for animal health drug filling and aseptic packaging lines.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExport \u0026amp; Regulated Markets:\u003c\/strong\u003e Machine design and GMP-compliant materials support compliance with WHO, EU GMP, FDA, and other international pharmaceutical manufacturing regulations.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ZONESUN","offers":[{"title":"220V","offer_id":52059438612768,"sku":null,"price":22399.0,"currency_code":"USD","in_stock":true},{"title":"380V","offer_id":52059438645536,"sku":null,"price":22399.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0776\/9250\/2304\/files\/8001_9a4d9815-fdb5-4516-96e2-9053dd678c1a.jpg?v=1785466787","url":"https:\/\/www.zonesunpro.com\/es\/products\/zonesun-zs-dm1-automatic-prefilled-syringe-denesting-machine","provider":"ZONESUNPRO","version":"1.0","type":"link"}